Use of require(lib) versus

I don't have a handle on when to use require('jslib') versus <script src=""></script> in Electron content pages (e.g. index.html). With jQuery, I discovered that it needs to be loaded as follows:

<script>window.$ = window.jQuery = require('./js/jquery-2.2.4.min.js');</script>

I need to start using some other libraries (e.g. Handlebars, ds3.js, Bootstrap, etc.) and I am not sure if I should be loading those with the <script> tag or if I should require them.

from Use of require(lib) versus