Raspberry Pi:4 Problem with pySerial and Screen touch function

i have quite specific SW / HW problem probably related with serial communication...

My project is based on Raspberry Pi 4 + 7" Touch screen + ESP32 microcontroller and i have problem with screen touch function.

Project detailed architecture:

1. on Raspberry Pi is running my application writen in Python 3 (+Kivy Framework) and reading data with pySerial library (source bellow)
2. touch screen is connected with HDMI(video) + USB(touch),
3. to next USB is connected development board with ESP32 microcontroler and pushing data via UART to Raspberry Pi

Data reading from ESP32 UART:

import serial
uart = serial.Serial(port="/dev/ttyUSB0", bytesize=8, baudrate=9600,
                     stopbits=1, timeout=0.2, parity='N')

Okey, and here is my problem:

When is connected only USB <-> UART data cable (touch screen isn't connected), everything works great: I am sending data from ESP32 microcontroller (over UART) and then reading it on Raspberry Pi with pySerial library (and vice versa: When i have connected touch screen and i don't have connected USB <-> UART cable, touch works fine too).

But when both USB Touch Screen and USB <-> UART are connected together, i cann't see any data from ESP32 microcontroller and of course, touch function isn't works...

Based on information written above, problem is probably with serial communication, respectively conflict between USB <->UART and USB touch interfaces but i don't have experience how to fix or rebuild it.

Please, do someone experience / knowledge how to solve it? (if i forgot write some important information, of course, i can it add it here)

from Raspberry Pi:4 Problem with pySerial and Screen touch function