How can I use nginx with adonis?

I'm try to make a deploy of one api adonis and I'm trying to use nginx to enable external access to my http requests.

I install nginx and go in ssh I go to:

cd /etc/nginx
vi nginx.conf

So, I put this code:

#user  nobody;
worker_processes  1;

#error_log  logs/error.log;
#error_log  logs/error.log  notice;
#error_log  logs/error.log  info;

#pid        logs/nginx.pid;


events {
    worker_connections  1024;
}


http {
    include       mime.types;
    default_type  application/octet-stream;

    #log_format  main  '$remote_addr - $remote_user [$time_local] "$request" '
    #                  '$status $body_bytes_sent "$http_referer" '
    #                  '"$http_user_agent" "$http_x_forwarded_for"';

    #access_log  logs/access.log  main;

    sendfile        on;
    #tcp_nopush     on;

    #keepalive_timeout  0;
    keepalive_timeout  65;

    #gzip  on;


    # another virtual host using mix of IP-, name-, and port-based configuration
    #
    #server {
    #    listen       8000;
    #    listen       somename:8080;
    #    server_name  somename  alias  another.alias;

    #    location / {
    #        root   html;
    #        index  index.html index.htm;
    #    }
    #}

    server {
        listen 80;

        server_name knowhowexpressapp.com ;

        location / {
            proxy_pass http://localhost:3333;
            proxy_http_version 1.1;
            proxy_set_header Upgrade $http_upgrade;
            proxy_set_header Connection 'upgrade';
            proxy_set_header Host $host;
            proxy_set_header X-Real-IP $remote_addr;
            proxy_set_header X-Forwarded-Proto $scheme;
            proxy_set_header X-Forwarded-For $proxy_add_x_forwarded_for;
            proxy_cache_bypass $http_upgrade;
        }
    }


    # HTTPS server
    #
    #server {
    #    listen       443 ssl;
    #    server_name  localhost;

    #    ssl_certificate      cert.pem;
    #    ssl_certificate_key  cert.key;

    #    ssl_session_cache    shared:SSL:1m;
    #    ssl_session_timeout  5m;

    #    ssl_ciphers  HIGH:!aNULL:!MD5;
    #    ssl_prefer_server_ciphers  on;

    #    location / {
    #        root   html;
    #        index  index.html index.htm;
    #    }
    #}

}

In server name I put the domain; In port I put 3333 because is the port that I put in .env;

I start nginx:

cd /usr/bin/etc/nginx
nginx

Check if nginx is running:

[root@knowhowexpressapp etc]# ps aux | grep nginx
root      14143  0.0  0.0  55320  1028 ?        Ss   11:41   0:00 nginx: master process nginx
nginx     14144  0.0  0.0  55708  1936 ?        S    11:41   0:00 nginx: worker process
root      14188  0.0  0.0 112712   964 pts/2    S+   11:42   0:00 grep --color=auto nginx

My .env archive:

HOST=ip from my server
PORT=3333
NODE_ENV=production
APP_NAME=AdonisJs
APP_URL=http://${HOST}:${PORT}
CACHE_VIEWS=false
APP_KEY=GPhustNKtbIlrxawTZa6xQTIkHcjBXFr
DB_CONNECTION=pg
DB_HOST=localhost
DB_PORT=5432
DB_USER=postgres
DB_PASSWORD=xxxx
DB_DATABASE=xxx
HASH_DRIVER=bcrypt

So, i check pm2 and my server is running:

⇆ PM2+ activated 
┌─────┬───────────┬─────────────┬─────────┬─────────┬──────────┬────────┬──────┬───────────┬──────────┬──────────┬──────────┬──────────┐
│ id  │ name      │ namespace   │ version │ mode    │ pid      │ uptime │ ↺    │ status    │ cpu      │ mem      │ user     │ watching │
├─────┼───────────┼─────────────┼─────────┼─────────┼──────────┼────────┼──────┼───────────┼──────────┼──────────┼──────────┼──────────┤
│ 0   │ server    │ default     │ 4.1.0   │ fork    │ 12586    │ 16m    │ 34   │ online    │ 0%       │ 41.0mb   │ root     │ disabled │

But when i try to access my api i'm getting:

Could not get any response There was an error connecting to https://knowhowexpressapp.com/login.

My server is centos 7

My api is only running if i put the http://ipfrommyserver but when i try to access the domain i receive error.

from How can I use nginx with adonis?