uwsgi: Send http response and continue execution

From the uwsgi documentation:

def application(env, start_response):
    start_response('200 OK', [('Content-Type','text/html')])
    return [b"Hello World"]

Is it possible to respond to http request(close http connection) and continue execution flow(without any usage of threads/queues/external services etc)? like this:

def application(env, start_response):
    start_response('200 OK', [('Content-Type','text/html')])
    end_response(b"Hello World")
    #HTTP connection is closed
    #continue execution..

from uwsgi: Send http response and continue execution